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1

[Methods in Enzymology] Lipidomics and Bioactive Lipids: Mass‐Spectrometry–Based Lipid Analysis Volume 432 || Lipidomic Analysis of Signaling Pathways

Wakelam, Michael J.O.

Year:

2007

Language:

english

File:

PDF, 161 KB

english, 2007

2

SnapShot: Lipid Kinases and Phosphatases

Rudge, Simon A., Wakelam, Michael J.O.

Journal:

Year:

2013

File:

PDF, 51 KB

2013

3

SnapShot: Lipid Kinase and Phosphatase Reaction Pathways

Rudge, Simon A., Wakelam, Michael J.O.

Journal:

Year:

2014

Language:

english

File:

PDF, 315 KB

english, 2014

4

The uses and limitations of the analysis of cellular phosphoinositides by lipidomic and imaging methodologies

Wakelam, Michael J.O.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2014

Language:

english

File:

PDF, 254 KB

english, 2014

5

Acetyl-coA synthetase 2 promotes acetate utilization and maintains cell growth under metabolic stress

Schug, Zachary, Peck, Barrie, Jones, Dylan, Zhang, Qifeng, Alam, Israt, Witney, Tim, Smethurst, Elizabeth, Grosskurth, Shaun, Harris, Adrian, Critchlow, Susan, Aboagye, Eric, Wakelam, Michael, Schulze

Journal:

Cancer & Metabolism

Year:

2014

Language:

english

File:

PDF, 84 KB

english, 2014

6

A nutritional memory effect counteracts the benefits of dietary restriction in old mice

Hahn, Oliver, Drews, Lisa F., Nguyen, An, Tatsuta, Takashi, Gkioni, Lisonia, Hendrich, Oliver, Zhang, Qifeng, Langer, Thomas, Pletcher, Scott, Wakelam, Michael J. O., Beyer, Andreas, Grönke, Sebastian

Journal:

Nature Metabolism

Year:

2019

File:

PDF, 13.47 MB

2019

7

Activation of vascular adhesion protein-1 on liver endothelium results in an NF-κB–dependent increase in lymphocyte adhesion

Patricia F. Lalor, Phoebe Jun Sun, Chris J. Weston, Azucena Martin-Santos, Michael J. O. Wakelam, David H. Adams

Journal:

Year:

2007

Language:

english

File:

PDF, 520 KB

english, 2007

8

Second-messenger pathways involved in the regulation of survival in germinal-centre B cells and in burkitt lymphoma lines

Kirstine A. Knox, Michael Finney, Anne E. Milner, Christopher D. Gregory, Michael J. O. Wakelam, Robert H. Michell, John Gordon

Journal:

International Journal of Cancer

Year:

1992

Language:

english

File:

PDF, 1.03 MB

english, 1992

9

Investigation of lipid signalling pathways by mass spectrometry

Qifeng Zhang, Michael Wakelam

Journal:

Chemistry and Physics of Lipids

Year:

2010

Language:

english

File:

PDF, 50 KB

english, 2010

10

Adipsin and the Glucose Transporter GLUT4 Traffic to the Cell Surface via Independent Pathways in Adipocytes

Caroline A. Millar, Timo Meerloo, Sally Martin, Gilles R.X. Hickson, Neil J. Shimwell, Michael J.O. Wakelam, David E. James, Gwyn W. Gould

Journal:

Year:

2000

Language:

english

File:

PDF, 655 KB

english, 2000

11

An intracellular motif of GLUT4 regulates fusion of GLUT4-containing vesicles

Catherine A Heyward, Trevor R Pettitt, Sophie E Leney, Gavin I Welsh, Jeremy M Tavaré, Michael JO Wakelam

Journal:

BMC Cell Biology

Year:

2008

Language:

english

File:

PDF, 1.64 MB

english, 2008

12

Confounding Effects of Benign Lung Diseases on Non-Small Cell Lung Cancer Serum Biomarker Discovery

Sridhar Rathinam, Aiman Alzetani, Jane Starczynski, Pala B. Rajesh, Stephen Nyangoma, Michael J. O. Wakelam, Nicholas D. James, Wenbin Wei, Lucinda J. Billingham, Philip J. Johnson, Ashley Martin, Dou

Journal:

Clinical Proteomics

Year:

2009

Language:

english

File:

PDF, 283 KB

english, 2009

13

Transmitter-like action of ATP on patched membranes of cultured myoblasts and myotubes

Kolb, Hans-Albert, Wakelam, Michael J. O.

Journal:

Year:

1983

File:

PDF, 353 KB

1983

14

Activation of two signal-transduction systems in hepatocytes by glucagon

Wakelam, Michael J. O., Murphy, Gregory J., Hruby, Victor J., Houslay, Miles D.

Journal:

Year:

1986

File:

PDF, 493 KB

1986

15

Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production

Wakelam, Michael J. O., Davies, Shireen A., Houslay, Miles D., McKay, Ian, Marshall, Christopher J., Hall, Alan

Journal:

Year:

1986

File:

PDF, 493 KB

1986

16

Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry

Clark, Jonathan, Anderson, Karen E, Juvin, Veronique, Smith, Trevor S, Karpe, Fredrik, Wakelam, Michael J O, Stephens, Len R, Hawkins, Phillip T

Journal:

Year:

2011

Language:

english

File:

PDF, 773 KB

english, 2011

17

The regulation by phosphorylation of ‘priming’ of phospholipase A2 activity in the neutrophil model system, differentiated HL60 cells

Allison Stewart, Clive G. Jackson, Michael J. O. Wakelam

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 404 KB

english, 1997

18

Breast cancer cell-derived EMMPRIN stimulates fibroblast MMP2 release through a phospholipase A2 and 5-lipoxygenase catalyzed pathway

Taylor, Paul M, Woodfield, Richard J, Hodgkin, Matthew N, Pettitt, Trevor R, Martin, Ashley, Kerr, David J, Wakelam, Michael JO

Journal:

Year:

2002

Language:

english

File:

PDF, 198 KB

english, 2002

19

Book reviews

Michael Wakelam, Gary Foster

Journal:

Molecular Biotechnology

Year:

1995

Language:

english

File:

PDF, 113 KB

english, 1995

20

Development of a novel, Ins(1,4,5)P3-specific binding assay: Its use to determine the intracellular concentration of Ins(1,4,5)P3 in unstimulated and vasopressin-stimulated rat hepatocytes

Susan Palmer, Kelvin T. Hughes, Denise Y. Lee, Michael J.O. Wakelam

Journal:

Cellular Signalling

Year:

1989

Language:

english

File:

PDF, 617 KB

english, 1989

21

v-Src Induces elevated levels of diglyceride by stimulation of phosphatidylcholine hydrolysis

Anne W. Wyke, Simon J. Cook, Elizabeth E. MacNulty, Michael J.O. Wakelam

Journal:

Cellular Signalling

Year:

1992

Language:

english

File:

PDF, 514 KB

english, 1992

22

Stimulated phosphatidylcholine hydrolysis as a signal transduction pathway in mitogenesis

Simon J. Cook, Michael J.O. Wakelam

Journal:

Cellular Signalling

Year:

1991

Language:

english

File:

PDF, 740 KB

english, 1991

23

Mechanical and biochemical responses to endothelin-1 and endothelin-3 in human bronchi

Jane E. Nally, Raymond McCall, Louise C. Young, Michael J.O. Wakelam, Neil C. Thomson, John C. McGrath

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1994

Language:

english

File:

PDF, 768 KB

english, 1994

24

Protein kinase C: Current concepts and future perspectives: edited by David S. Lester and Richard M. Epand, Ellis Horwood, 1992. £59.00 (ix + 365 pages) ISBN 13 720186 9

Michael J.O. Wakelam

Journal:

Trends in Cell Biology

Year:

1993

Language:

english

File:

PDF, 150 KB

english, 1993

25

Determination of phospholipase D, lysophospholipase D and DG kinase signaling pathways in disease states by mass spectrometry

Michael J.O. Wakelam, Dale J. Powner, Trevor R. Pettitt

Journal:

Advances in Enzyme Regulation

Year:

2008

Language:

english

File:

PDF, 145 KB

english, 2008

26

Cross-talk between phospholipase D and MAP kinases activities

Michael J.O. Wakelam, Gavin S. McNee, Simon A. Rudge

Journal:

Advances in Enzyme Regulation

Year:

2010

Language:

english

File:

PDF, 129 KB

english, 2010

27

PLCγ is enriched on poly-phosphoinositide-rich vesicles to control nuclear envelope assembly

Richard D. Byrne, Marie Garnier-Lhomme, Kevin Han, Michael Dowicki, Nick Michael, Nick Totty, Vanessa Zhendre, Aeri Cho, Trevor R. Pettitt, Michael J. Wakelam, Dominic L. Poccia, Banafshé Larijani

Journal:

Cellular Signalling

Year:

2007

Language:

english

File:

PDF, 1.02 MB

english, 2007

28

Stimulation of actin stress fibre formation mediated by activation of phospholipase D

Michael J. Cross, Sally Roberts, Anne J. Ridley, Matthew N. Hodgkin, Allison Stewart, Lena Claesson- Welsh, Michael J.O. Wakelam

Journal:

Current Biology

Year:

1996

Language:

english

File:

PDF, 974 KB

english, 1996

29

Phospholipase D1 localises to secretory granules and lysosomes and is plasma-membrane translocated on cellular stimulation

Fraser D. Brown, Nicola Thompson, Khalid M. Saqib, Joanna M. Clark, Dale Powner, Neil T. Thompson, Roberto Solari, Michael J.O. Wakelam

Journal:

Current Biology

Year:

1998

Language:

english

File:

PDF, 312 KB

english, 1998

30

Phospholipase D regulation and localisation is dependent upon a phosphatidylinositol 4,5-bisphosphate-specific PH domain

Matthew N. Hodgkin, Margaret R. Masson, Dale Powner, Khalid M. Saqib, Christopher P. Ponting, Michael J.O. Wakelam

Journal:

Current Biology

Year:

2000

Language:

english

File:

PDF, 149 KB

english, 2000

31

Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?

Matthew N Hodgkin, Trevor R Pettitt, Ashley Martin, Robert H Michell, Anthony J Pemberton, Michael J.O Wakelam

Journal:

Trends in Biochemical Sciences

Year:

1998

Language:

english

File:

PDF, 477 KB

english, 1998

32

Evaluation of the accuracy of serum MMP-9 as a test for colorectal cancer in a primary care population

Sue Wilson, Michael JO Wakelam, Richard FD Hobbs, Angela V Ryan, Janet A Dunn, Val D Redman, Fiona Patrick, Lynne Colbourne, Ashley Martin, Tariq Ismail

Journal:

Year:

2006

Language:

english

File:

PDF, 253 KB

english, 2006

33

A prospective study to assess the value of MMP-9 in improving the appropriateness of urgent referrals for colorectal cancer

Angela V Ryan, Sue Wilson, Michael JO Wakelam, Sally A Warmington, Janet A Dunn, Richard FD Hobbs, Ashley Martin, Tariq Ismail

Journal:

Year:

2006

Language:

english

File:

PDF, 220 KB

english, 2006

34

Establishing the added benefit of measuring MMP9 in FOB positive patients as a part of the Wolverhampton colorectal cancer screening programme

Sue Wilson, Taina Taskila, Tariq Ismail, Deborah D Stocken, Ashley Martin, Val Redman, Michael Wakelam, Ian Perry, Richard Hobbs

Journal:

Year:

2009

Language:

english

File:

PDF, 167 KB

english, 2009

35

Thyroid Hormones and the Precocious Induction of Hepatic Glucokinase in the Neonatal Rat

Michael J. O. WAKELAM, M. Bruce ALLEN, Deryck G. WALKER, Carmen ARAGON, Cecilio GIMENEZ

Journal:

Year:

1979

Language:

english

File:

PDF, 760 KB

english, 1979

36

PTEN Mutations as a Cause of Constitutive Insulin Sensitivity and Obesity

Pal, Aparna, Barber, Thomas M., Van de Bunt, Martijn, Rudge, Simon A., Zhang, Qifeng, Lachlan, Katherine L., Cooper, Nicola S., Linden, Helen, Levy, Jonathan C., Wakelam, Michael J.O., Walker, Lisa, K

Journal:

New England Journal of Medicine

Year:

2012

Language:

english

File:

PDF, 1.22 MB

english, 2012

37

3T3-L1 Adipocytes Express Two Isoforms of Phospholipase D in Distinct Subcellular Compartments

Caroline A. Millar, Thomas J. Jess, Khalid M. Saqib, Michael J.O. Wakelam, Gwyn W. Gould

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 91 KB

english, 1999

38

Introduction: Signal activated phospholipases

Michael J.O. Wakelam

Journal:

Seminars in Cell & Developmental Biology

Year:

1997

Language:

english

File:

PDF, 35 KB

english, 1997

39

Phospholipase D

Michael J.O. Wakelam, Matthew N. Hodgkin, Ashley Martin, Khalid Saqib

Journal:

Seminars in Cell & Developmental Biology

Year:

1997

Language:

english

File:

PDF, 88 KB

english, 1997

40

De novo synthesis of glucokinase in hepatocytes isolated from neonatal rats

Michael J.O. Wakelam, Deryck G. Walker

Journal:

Year:

1980

Language:

english

File:

PDF, 418 KB

english, 1980

41

L6 skeletal muscle cells have functional V1-vasopressin receptors coupled to stimulated inositol phospholipid metabolism

Michael J.O. Wakelam, Scan Patterson, Michael R. Hanley

Journal:

Year:

1987

Language:

english

File:

PDF, 315 KB

english, 1987

42

Inhibition of the amplified bombesin-stimulated inositol phosphate response in N-ras transformed cells by high density culturing

Michael J.O. Wakelam

Journal:

Year:

1988

Language:

english

File:

PDF, 383 KB

english, 1988

43

Widespread distribution of Gqα/Gllα detected immunologically by an antipeptide antiserum directed against the predicted C-terminal decapeptide

Fiona M. Mitchell, lan Mullaney, Philip P. Godfrey, Steve J. Arkinstall, Michael J.O. Wakelam, Graeme Milligan

Journal:

Year:

1991

Language:

english

File:

PDF, 581 KB

english, 1991

44

Heterologous desensitization of bombesin- and vasopressin-stimulated phospholipase D activity in Swiss 3T3 fibroblasts

Celia P. Briscoe, Michael J.O. Wakelam

Journal:

Year:

1995

Language:

english

File:

PDF, 472 KB

english, 1995

45

Inter-regulatory dynamics of phospholipase D and the actin cytoskeleton

Simon A. Rudge, Michael J.O. Wakelam

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2009

Language:

english

File:

PDF, 456 KB

english, 2009

46

Methods for analyzing phosphoinositides using mass spectrometry

Michael J.O. Wakelam, Jonathan Clark

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2011

Language:

english

File:

PDF, 440 KB

english, 2011

47

The search for new targets for cancer chemotherapeutics

Simon J Cook, Michael Wakelam

Journal:

Current Opinion in Pharmacology

Year:

2005

Language:

english

File:

PDF, 61 KB

english, 2005

48

Stable adhesion and migration of human neutrophils requires phospholipase D-mediated activation of the integrin CD11b/CD18

Dale J. Powner, Trevor R. Pettitt, Rhodri Anderson, Gerard B. Nash, Michael J.O. Wakelam

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 761 KB

english, 2007

49

lazaro Encodes a Lipid Phosphate Phosphohydrolase that Regulates Phosphatidylinositol Turnover during Drosophila Phototransduction

Isaac Garcia-Murillas, Trevor Pettitt, Elaine Macdonald, Hanneke Okkenhaug, Plamen Georgiev, Deepti Trivedi, Bassam Hassan, Michael Wakelam, Padinjat Raghu

Journal:

Year:

2006

Language:

english

File:

PDF, 747 KB

english, 2006

50

Diacylglycerol – when is it an intracellular messenger?

Michael J.O Wakelam

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

1998

Language:

english

File:

PDF, 212 KB

english, 1998